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. 2021 Oct 29;153(2):167–174. doi: 10.1016/j.adaj.2021.08.007

Table.

Signs and symptoms associated with long COVID, medications routinely used in the treatment of these findings, their impact on oral health care interventions, and treatment modifications recommended for patients.

SIGNS AND SYMPTOMS MEDICATIONS IMPACT ON ORAL HEALTH CARE INTERVENTION TREATMENT MODIFICATION
Fatigue NA Decreased ability to withstand treatment Short appointments, work with patient on timing and length of appointments
Shortness ofBreath Supplementary oxygen, systemic corticosteroids, bronchodilators, β2-agonists Decreased mobility, decreased functional capacity Pulse oximetry monitoring, monitoring for infection, patients should be instructed to bring any supplemental oxygen and new inhaled medications
ChestPain NA If present, discontinue treatment Symptom monitoring
HeartFailure NA Decreased functional capacity Caution with chair positioning, confirm ability to tolerate planned procedure
VenousThromboembolism Antiplatelet and anticoagulant medications Possible prolonged or excessive bleeding Monitor hemostasis, apply local measures as needed, provide breaks, short appointments to prevent new thrombus formation
Seizures NA May lead to weakness, paralysis, paresthesia Monitor for signs and symptoms, adjust home care according to functional capacity
MuscleWeakness NA Changes in balance and gait may affect ingress and egress from dental operatory Caution with ingress and egress
PosturalOrthostaticTachycardia NA May be exacerbated by changes during the positioning of the dental chair Avoid rapid chair positioning and confirm patient tolerance of position
NeuropathicPain andHeadache Triptans Can affect the orofacial region May require evaluation and treatment by orofacial pain specialists
CognitiveChanges NA May show reduced memory and ability to make decisions If necessary, involve other decision makers, ensure informed consent
PsychiatricIllness Antianxiety and antidepressive medications Inability to submit to care, decreased reliability Treatment of patient concerns, understanding, monitoring and treatment of decreased salivary flow and resultant caries and periodontal disease
ChronicPain Possibly treated with habit-forming medications including opioids Inability to tolerate prolonged procedures and certain positions Short appointments and adjustments to patient needs, positioning and breaks as needed, avoid provision of opioid analgesics
KidneyImpairment NA Decreased metabolism of medications eliminated in the kidneys Changes in dose and timing according to kidney function
HepaticImpairment NA Decreased metabolism of hepatically processed medications Changes in dose and timing, avoid hepatically metabolized medications as possible

NA: Not applicable.