Fig. 5.

Manhattan plot for PV in imputed SNPs from the region surrounding the copy number variant esv3624175. The region shown encompasses $\pm 500$ Kb from rs75297609 and rs57205007. Its physical coordinates are 10:91521574-92510199. Genome-wide association P values are expressed as − log${}_{10}$(P-value). Highlighted in blue is rs7919344-T, the significantly associated variant allele located within esv3624175. All variants mapping esv3624175 are labeled in blue. Variants with association P value $<{10}^{-5}$ (Table 2) also map esv3624175 (not shown)