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. 2021 Oct 27;7:101. doi: 10.1038/s41421-021-00343-5

Fig. 1. Long-term psychological stress induces paternal inheritance of health risks in offspring.

Fig. 1

a Chronic restraint stress mouse model construction. b Stress-induced transgenerational inheritance of developmental retardation. c Stress-induced transgenerational inheritance of disorder in blood glucose metabolism. d Elevated plus maze (EPM) test to assess anxiety-like behavior in mice. Stress-induced intergenerational inheritance of higher risk-taking behavior and overall physical activity. e Stress-induced transgenerational inheritance of decline in sperm concentration decline. f Stress-induced transgenerational inheritance of reduced in sperm motility. g Stress-induced transgenerational inheritance of reduced in fertility rate. *t-test p-value < 0.05; **t-test p-value < 0.01; n.s. no significant, t-test p-value > 0.05.