Table 3:
Summary of results (N = 335)
| Outcome/effect | DF+EAF group | DF group | β | 95% CI | p value |
|---|---|---|---|---|---|
| (n=164) | (n=171) | ||||
| M (SD) | M (SD) | ||||
| Time 2 | |||||
| Test-related distress | 0.39 (0.81) | 0.58 (0.91) | −0.20 | −0.40, −0.01 | 0.043 |
| Test-related positive experiences | 1.76 (1.43) | 1.73 (1.34) | 0.01 | −0.30, 0.33 | 0.934 |
| Test-related uncertainty | 0.92 (0.82) | 1.13 (0.95) | −0.22 | −0.42, −0.02 | 0.035 |
| Generalized anxiety | 5.20 (3.70) | 6.04 (4.38) | −0.74 | −1.38, −0.09 | 0.025 |
| Depressive symptoms | 4.40 (3.37) | 4.63 (4.06) | −0.11 | −0.73, 0.51 | 0.730 |
| Decision regret | 1.48 (0.55) | 1.47 (0.55) | −0.002 | −0.13, 0.12 | 0.978 |
| Information seeking difficulty | 2.31 (0.77) | 2.26 (0.81) | 0.05 | −0.13, 0.23 | 0.583 |
| Self-reported healthcare utilization | 0.08 (0.04) | 0.08 (0.04) | −0.004 | −0.012, 0.004 | 0.281 |
| Time 3 | |||||
| Test-related distress | 0.35 (0.83) | 0.39 (0.71) | −0.04 | −0.22, 0.14 | 0.671 |
| Test-related positive experiences | 2.46 (1.60) | 2.70 (1.56) | −0.32 | −0.69, 0.05 | 0.093 |
| Test-related uncertainty | 0.74 (0.84) | 0.80 (0.84) | −0.08 | −0.27, 0.12 | 0.451 |
| Generalized anxiety | 5.54 (3.99) | 6.20 (4.52) | −0.55 | −1.29, 0.18 | 0.141 |
| Depressive symptoms | 4.43 (3.48) | 4.90 (4.14) | −0.41 | −1.05, 0.24 | 0.221 |
| Decision regret | 1.53 (0.57) | 1.49 (0.52) | 0.04 | −0.08, 0.17 | 0.497 |
| Self-reported healthcare utilization | 0.16 (0.11) | 0.18 (0.13) | −0.02 | −0.04, 0.01 | 0.244 |
| Time 4 | |||||
| Test-related distress | 0.36 (0.85) | 0.36 (0.65) | −0.01 | −0.19, 0.17 | 0.916 |
| Test-related positive experiences | 2.36 (1.73) | 2.67 (1.72) | −0.38 | −0.79, 0.03 | 0.070 |
| Test-related uncertainty | 0.75 (0.89) | 0.78 (0.91) | −0.06 | −0.27, 0.16 | 0.595 |
| Generalized anxiety | 5.43 (3.83) | 5.71 (4.52) | −0.15 | −0.83, 0.54 | 0.679 |
| Depressive symptoms | 4.26 (3.52) | 4.44 (4.05) | −0.07 | −0.77, 0.64 | 0.854 |
| Decision regret | 1.56 (0.62) | 1.49 (0.54) | 0.09 | −0.05, 0.24 | 0.193 |
| Self-reported healthcare utilization | 0.15 (0.09) | 0.15 (0.10) | 0.001 | −0.02, 0.02 | 0.945 |
DF = Group that received Diagnostic Findings only. DF+EAF = Group that received Diagnostic Findings + Additional Findings Education along with option to request additional genomic findings.