TABLE 2.
Comparison of diagnostic performances of the VCA IgG and VCA IgM (indirect) ELISAs based on GST-p18, p23, and p23-p18
| ELISA (indirect) | Cutoff [OD] | Sera from patients with:
|
Seronegatives (n = 7)
|
|||||
|---|---|---|---|---|---|---|---|---|
| Primary infections (n = 22)
|
Previous infections (n = 102)
|
|||||||
| No. pos.a | Sensitivity (%) | No. pos. | Sensitivity (%) | Specificity (%) | No. pos. | Specificity (%) | ||
| GST-p18 IgG | 0.20 | 12 | 54.5 | 99 | 97.1 | 0 | 100.0 | |
| p23 IgG | 0.15 | 17 | 77.3 | 95 | 93.1 | 0 | 100.0 | |
| p23-p18 IgG | 0.20 | 18 | 81.8 | 101 | 99.0 | 0 | 100.0 | |
| GST-p18 IgM | 0.40 | 22 | 100.0 | 1 | 99.9 | 0 | 100.0 | |
| p23 IgM | 0.20 | 8 | 36.4 | 0 | 100.0 | 0 | 100.0 | |
| p23-p18 IgM | 0.40 | 22 | 100.0 | 0 | 100.0 | 0 | 100.0 | |
pos., positive.