Table 3:

miRNA expression patterns during skin wound healing and their regulation of various aspects of the process.

miRNA	Process	References
miR-155	Down regulation via AS ODNs can improve efficiency and quality of skin wound healing by reducing inflammation	[190] [191]
miR-21	(a) Upregulated in epithelial cells at the initiation of beginning of cell migration at wound site. (b) Down-regulation delayed wound healing from 1–14 days after injury. (c) Over-expression via lentivirus facilitated the improved healing in rat model targeting Pten gene	[178],[192]
miR-146 a miR-106b	(a) Prevent the skin infection during wound healing	[193]
miR-200c	(a) Overexpression delayed re-epithelialization in human skin model	[194]
miR-210	(a) Downregulation embargo skin re-epithelialization	[195]
miR-15b, miR26a, miR-92a, miR-200b,	(a) Down regulation Improved skin healing in diabetes patients	[196]
miR-132, miR27b	(a) Downregulation improved skin wound healing in diabetes patients	[197][198]
miR29b and miR-1908	(a) Overexpression inhibit scarring	[199] [200]
miR-132	(a) enhance the transition from inflammation to proliferation during wound healing	[201]
miR-142	(a) neutrophils to clear S. aureus infected-skin wound sites	[202]
Let-7b	(a) overexpression exhibit a delay in re-epithelialization at wound site	[203]
miR-198	(a) inhibits keratinocytes migration and proliferation	[211], [212]
miR-23b	(a) cutaneous wound healing via inhibition of inflammatory reactions	[213]
miR-483-3p	(a) controls proliferation in wounded epithelial cells	[214]