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. 2021 Oct 28;12:6228. doi: 10.1038/s41467-021-26352-2

Table 1.

Absence of Itgβ8 on Tregs represses tumor growth.

Melanoma Breast cancer
Genotype Foxp3Ctr Foxp3ΔItgβ8 Foxp3Ctr Foxp3ΔItgβ8
Number of mice 16 16 16 16
Number of mice with non-measurable tumor 0 4 1 8
Percentage of mice with non-measurable tumor (0%) (25%) (6.25%) (50%)

Foxp3ΔItgβ8 mice and their littermate controls (Foxp3Ctrl) were injected either i.d. with melanoma (B16 cells) or in the mammary gland with breast cancer (E0771 cells). Table showing the percentage of Foxp3ΔItgβ8 mice and Foxp3WT mice with a completed control of tumor growth (tumor < 100 mm3 all along the experiments) for both melanoma and breast cancer 18 days after implantation.