Skip to main content
. 2021 Oct 28;7:318. doi: 10.1038/s41420-021-00720-9

Fig. 6. Effect of miR548ai inhibitor on AoSMC proliferation and migration.

Fig. 6

A Schematic of the experimental design for this figure. B SMC proliferation in full medium. AoSMCs cultured in the full medium were transfected with miR548ai mimic or inhibitor or scrambled microRNA (control) prior to CellTiter-Glo assay. C SMC migration in full medium. AoSMCs cultured in the full medium were transfected with miR548ai inhibitor or scrambled microRNA (control) prior to the Transwell migration assay. D SMC proliferation in defined medium. Starved AoSMCs were transfected with miR548ai inhibitor or scrambled control prior to stimulation with PDGF-BB, TGFβ1, TNFα, or IL1β (same concentrations as indicated in Fig. 1). Data are presented as mean ± SD (n = 3 replicates). Student t-test: *P < 0.05, **P < 0.01; NS not significant.