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. 2021 Oct 15;12:759249. doi: 10.3389/fphar.2021.759249

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Copyright © 2021 Morino, Sugimoto, Nagata, Niikiura, Iwata, Hamada, Kawai, Fujimiya, Takeuchi, Unezaki and Kawai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Forest plots of H. pylori cure rates of LPZ-amoxicillin-clarithromycin regimen among different CYP2C19 genotypes in the fixed-effects model. (A) CYP2C19 EMs vs IMs, (B) EMs vs PMs and (C) IMs and PMs.; Abbreviations: CI, confidence interval; EM, extensive metabolizer of CYP2C19; IM, intermediate metabolizer of CYP2C19; LPZ, lansoprazole; PPI, proton pump inhibitor; PM, poor metabolizer of CYP2C19; PPI, proton pump inhibitor.