Table 3.
Level of inflammatory factor and vitreous 25 (OH) D in PDR patients according to pan-retinal laser photocoagulation state.
| Non-PRP (n = 27) | IRP (n = 9) | PRP (n = 19) | P -value | |||
|---|---|---|---|---|---|---|
| P a | P b | P c | ||||
| NLRP3 (ng/mL) | 0.05 ± 0.01 | 0.04 ± 0.01 | 0.04 ± 0.00 | 0.0752 | 0.0017 | >0.99 |
| VVD (ng/mL) | 17.67 ± 2.88 | 18.62 ± 3.76 | 18.78 ± 2.50 | >0.99 | 0.3051 | >0.99 |
| Caspase-1 (pg/mL) | 49.68 ± 10.71 | 45.77 ± 9.46 | 36.60 ± 11.96 | >0.99 | 0.0006 | 0.1141 |
| IL-1β (pg/mL) | 31.56 ± 5.65 | 30.56 ± 5.37 | 24.70 ± 4.96 | >0.99 | 0.0003 | 0.0673 |
| VEGF (pg/mL) | 394.40 ± 80.45 | 341.80 ± 41.37 | 292.30 ± 55.52 | 0.4580 | <0.0001 | 0.0971 |
a
P, Non-PRP vs. IRP;
b
P, Non-PRP vs. PRP;
c
P, IRP vs. PRP.
Data are shown as mean ± SD. P < 0.05 was considered statistically significant.
PRP, pan retinal photocoagulation; IRP, incomplete retinal laser photocoagulation; VVD, vitreous 25 (OH) D; IL-1β, interleukin-1β; VEGF, vascular endothelial growth factor.