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Longitudinal trend of systolic blood pressure change with gestational age vs. early-pregnancy biomarkers levels, predicted by linear mixed-effects regression models. (A) lactate dehydrogenase (LDH); (B) aspartate aminotransferase to alanine aminotransferase ratio (AST/ALT); (C) gamma-glutamyl transpeptidase (GGT); (D) alkaline phosphatase (ALP); (E) uric acid (UA); (F) estimated glomerular filtration rate (eGFR).
