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. 2021 Oct 15;12:706610. doi: 10.3389/fneur.2021.706610

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Copyright © 2021 Pennati, Bergling, Carment, Borg, Lindberg and Palmcrantz.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Individual changes in NeuroFlexor neural component in the upper extremity during and after stimulation with EXOPULSE Mollii, graphically presented by type of response (Delta_A−B NC). A high variability of the EXOPULSE Mollii effect on NeuroFlexor neural component (NC, in Newton, N) was observed at individual level. Three patients out of 20 presented a negative Delta_A−B NC (i.e., the difference in NC between after stimulation value and before stimulation value) in OFF-settings, six patients at 20 Hz and eight at 30 Hz. To notice, NC before electrical stimulation was >14 N for OFF-settings, >13 N for 20 Hz and >8 N for 30 Hz among these patients. Nine patients presented a positive Delta_A−B NC in OFF-settings, 11 patients at 20 Hz and seven patients at 30 Hz. Delta_A−B NC within the margin of measurement error of 1 N was considered stable.