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. 2021 Oct 15;9:753706. doi: 10.3389/fcell.2021.753706

TABLE 3.

Information of DANCR in breast cancer from six research articles.

Role of DANCR DANCR expression in BC cell lines Compared normal cell line In vitro/in vivo validation Tissue sample size DANCR expression in tissues References
Tumorigenesis ↑:
MCF7, T47D,
MDA-MB-231,
MDA-MB-468
Hs578Bst Both 63 (TNBC)/63 (ANT) ↑: P = 0.009 Sha et al., 2017
Tumorigenesis ↑:
MCF7, T47D, BT549,
MDA-MB-231,
MDA-MB-468,
MDA-MB-453
MCF10A Both 60 (TNBC)/10 (normal breast tissue); 60 (TNBC)/15 (Luminal A); 60 (TNBC)/15 (Luminal B) ↑: P < 0.001;
↑:
P < 0.05;
↑:
P < 0.01
Tang et al., 2018
Tumorigenesis ↑:
MCF7,
MDA-MB-231
MCF10A Both 57 (TNBC)/57 (ANT) ↑: P < 0.05 Tao et al., 2019
Tumorigenesis ↑:
MCF7, T47D,
MDA-MB-231,
MDA-MB-468
MCF10A Both 46 (BC)/46 (ANT) ↑: P < 0.01 Zhang K.J. et al., 2020
Tumor suppression ↓:
MCF7, T47D, BT474,
MDA-MB-436,
MDA-MB-231,
MDA-MB-231HM
MCF10A Both 32 (BC)/32 (ANT) ↓: P < 0.0001 Li et al., 2017c
Tumor suppression ↓:
MCF7, T47D,
MDA-MB-231HM
↑:
BT549
MCF10A Both 25 (BC)/25 (ANT) ↓ (P-value was not provided) Li et al., 2017b