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. 2021 Oct 13;28:26–33. doi: 10.1016/j.jor.2021.10.005

Table 5.

Multivariate logistic regression analysis of hospital outcomes in comparison to patients not receiving multimodal analgesia.

Multimodal Group Odds Ratio OR 95% CI P-Value
Outcome: Hospital LOS ≥2 Days
Group 2 Acetaminophen Only 0.464 0.262–0.822 0.009
Group 3 Acetaminophen with Pregabalin/Gabapentin Only 0.360 0.223–0.580 <0.001
Group 4 Celecoxib with Acetaminophen or Pregabalin/Gabapentin 0.164 0.049–0.553 0.004
Group 5 Full Multimodal – Celecoxib, Acetaminophen, and Pregabalin/Gabapentin 0.398 0.269–0.590 <0.001
Outcome: Hospital OMME ≥ 75thPercentile
Group 2 Acetaminophen Only 0.558 0.357–0.871 0.010
Group 3 Acetaminophen with Pregabalin/Gabapentin Only 0.375 0.262–0.535 <0.001
Group 4 Celecoxib with Acetaminophen or Pregabalin/Gabapentin 0.524 0.272–1.009 0.053
Group 5 Full Multimodal – Celecoxib, Acetaminophen, and Pregabalin/Gabapentin 0.351 0.258–0.478 <0.001

P-Value <0.05 in bold.

Adjusted Odds Ratio controlling for age, BMI, non-white race, diabetes mellitus, CAD, GERD, ASA ≥3, spinal anesthesia.