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. 2021 Oct 15;11:730638. doi: 10.3389/fonc.2021.730638

Table 5.

Correlation analysis of differential metabolites and commonly used fasting lipid profiles.

Biomarker TC (r, p) TG (r, p) HDL-C (r, p) LDL-C (r, p) Apo-A1 (r, p) Apo-B (r, p)
4-Oxoretinol −0.578, <0.001 0.031, 0.794 −0.242, 0.038 −0.502, <0.001 −0.241, 0.038 −0.313, 0.007
Anandamide −0.542, <0.001 0.033, 0.782 −0.245, 0.035 −0.571, <0.001 −0.214, 0.067 −0.376, 0.001
Palmitic acid −0.561, <0.001 −0.094, 0.426 −0.255, 0.028 −0.544, <0.001 −0.294, 0.011 −0.481, <0.001
Glycerol 1-hexadecanoate −0.591, <0.001 −0.027, 0.822 −0.295, 0.011 −0.440, <0.001 −0.354, 0.002 −0.285, 0.014
dl-Dihydrosphingosine −0.283, 0.015 −0.057, 0.631 −0.076, 0.519 −0.412, <0.001 −0.083, 0.483 −0.429, <0.001
2-Methoxy-6Z-hexadecenoic acid −0.587, <0.001 −0.079, 0.504 −0.215, 0.066 −0.527, <0.001 −0.295, 0.011 −0.424, <0.001
3-Oxo-nonadecanoic acid −0.582, <0.001 −0.081, 0.491 −0.246, 0.035 −0.463, <0.001 −0.329, 0.004 −0.324, 0.005
2-Hydroxy-nonadecanoic acid −0.566, <0.001 −0.092, 0.436 −0.269, 0.020 −0.435, <0.001 −0.359, 0.002 −0.280, 0.016
N-Palmitoyl glycine −0.524, <0.001 −0.076, 0.521 −0.223, 0.056 −0.459, <0.001 −0.240, 0.039 −0.314, 0.007
2-Palmitoylglycerol −0.483, <0.001 −0.174, 0.139 −0.191, 0.103 −0.459, <0.001 −0.277, 0.017 −0.360, 0.002
Hexadecenal −0.576, <0.001 −0.124, 0.291 −0.272, 0.019 −0.461, <0.001 −0.319, 0.006 −0.304, 0.008
d-Erythro-sphingosine C-15 −0.569, <0.001 −0.122, 0.299 −0.225, 0.054 −0.445, <0.001 −0.266, 0.022 −0.361, 0.002
N-Methyl arachidonoyl amine −0.552, <0.001 −0.055, 0.641 −0.242, 0.038 −0.475, <0.001 −0.281, 0.015 −0.279, 0.016
9-Octadecenal −0.461, <0.001 −0.150, 0.203 −0.063, 0.596 −0.489, <0.001 −0.111, 0.347 −0.445, <0.001
Hexadecyl acetyl glycerol −0.474, <0.001 −0.038, 0.746 −0.242, 0.038 −0.426, <0.001 −0.280, 0.016 −0.326, 0.005
PA (15:1(9Z)/20:0) −0.549, <0.001 0.067, 0.570 −0.283, 0.015 −0.458, <0.001 −0.231, 0.047 −0.305, 0.008
3Z,6Z,9Z-Octadecatriene −0.416, <0.001 −0.024, 0.839 −0.075, 0.525 −0.409, <0.001 −0.069, 0.561 −0.360, 0.002
Glycidyl stearate −0.463, <0.001 −0.152, 0.196 −0.066, 0.575 −0.484, <0.001 −0.124, 0.292 −0.484, <0.001

TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol.