FIGURE 2.

Differential expression profile of microRNA (miRNA) between degenerative menisci with and without IL-1β stimulation. (A) Hierarchical clustering illustrates distinguished expression difference of miRNA between the two groups and homogeneity between groups. (B) Relative expression level of selected mRNAs in negative control versus IL-1β-treated osteoarthritis (OA) menisci. U6 was used as the internal reference gene for qRT-PCR relative expression. Error bars reveal the standard deviation or the standard error of the data. The statistical methods are described above. *p < 0.05, **p < 0.01, ***p < 0.001.