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. 2021 Oct 15;12:759323. doi: 10.3389/fimmu.2021.759323

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Copyright © 2021 Wu, Li, Liu, Liu, Xu, Zhang, Yu, Wang and Yang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of Sphingolipid metabolism pathway. LPS: fed with a basal diet and injected with 0.5 mg/kg LPS; ANT+LPS: fed with a basal diet supplemented with 75 mg/kg ANT, and injected with 0.5 mg/kg LPS; LA+LPS: fed with a basal diet supplemented with 1000 mg/kg LA, and injected with 0.5 mg/kg LPS. N=6 in each group. (A) Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway map of Sphingolipid metabolism (map00600). The red nodes represent the differential metabolites. (B) Analysis of the differential metabolites by one-way ANOVA and Tukey’s test. *P < 0.05, **P < 0.01, ***P < 0.001.