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. 2021 Oct 15;12:759323. doi: 10.3389/fimmu.2021.759323

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Copyright © 2021 Wu, Li, Liu, Liu, Xu, Zhang, Yu, Wang and Yang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of the diversity and composition of gut microbiota. LPS: fed with a basal diet and injected with 0.5 mg/kg LPS; ANT+LPS: fed with a basal diet supplemented with 75 mg/kg ANT, and injected with 0.5 mg/kg LPS; LA+LPS: fed with a basal diet supplemented with 1000 mg/kg LA, and injected with 0.5 mg/kg LPS. N=8 in each group. (A) Venn diagram presenting the operational taxonomic units (OTUs) from each group. (B) Shannon index of OTU level reflecting the α diversity. (C) β diversity shown in a Principal component analysis (PCA) scatterplot. (D) Bar graph of microbial composition at the genus level. (E) Box plot of the significant genera among groups. (F) Circos diagram indicating the dominant genera in each group. The data were analyzed by one-way ANOVA and Tukey’s test. *P < 0.05, **P < 0.01.