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. 2021 Oct 15;12:750489. doi: 10.3389/fmicb.2021.750489

Table 2.

Detailed susceptibility results for the 17 CF MRSA strains that were classified as strongly adherent/strong biofilm producers according to the Biofilm Ring Test® assay.

Patient Strain ST BFI Ceftaroline Ceftobiprole Linezolid Rifampicin Trimethoprim
MIC bMIC MIC bMIC MIC bMIC MIC bMIC MIC bMIC
1 1.1 8 4 <0.125 2 <0.25 16 <0.5 16 2 >2 1 >32
5 5.2 5 0.12 <0.125 <0.125 <0.25 <0.25 32 >64 2 >2 0.5 >32
5.3 5 0.75 <0.125 4 <0.25 8 16 32 2 >2 1 >32
6 6.3 5 0.58 <0.125 0.25 <0.25 2 1 16 2 >2 1 >32
6.4 5 0.25 0.25 0.25 <0.25 <0.25 16 >64 2 1 1 >32
7 7.2 5 0.71 0.25 0.25 <0.25 2 <0.5 2 0.5 >2 0.5 8
17 17.6 5 0 <0.125 4 <0.25 4 <0.5 2 2 >2 0.5 >32
18 18.2 8 3.03 <0.125 0.5 <0.25 2 1 1 2 >2 1 8
20 20.1 5828 0.66 <0.125 4 <0.25 4 1 64 2 >2 2 >32
25 25.5 5 4 0.25 0.25 <0.25 <0.25 2 2 <0.015 <0.015 2 32
25.6 5 3.22 <0.125 0.25 <0.25 8 4 4 <0.015 >2 0.5 >32
26 26.1 8 2.08 <0.125 <0.125 <0.25 2 <0.5 2 <0.015 0.015 <0.25 >32
28 28.3 5 0 <0.125 1 <0.25 2 <0.5 <0.5 2 >2 <0.25 >32
28.4 5 0.25 <0.125 <0.125 <0.25 <0.25 <0.5 1 <0.015 <0.015 <0.25 8
30 30.1 5 0 <0.125 <0.125 <0.25 <0.25 <0.5 1 <0.015 >2 1 32
31 31.2 8 2.68 <0.125 <0.125 <0.25 0.5 <0.5 1 2 >2 0.5 >32
32 32.1 8 1.89 <0.125 <0.125 <0.25 <0.25 1 1 2 >2 0.5 >32

Minimum inhibitory concentrations (MIC) and biofilm MIC (bMIC) in mg/L. MICs were determined according to the reference dilution method. bMICs were determined in filtered ASM. Gray cells indicate MIC and bMIC values above the EUCAST breakpoints for resistance (indicated in footnotes of Table 1). ST, sequence type. BFI, biofilm formation index.