Table 3.
Top 20 mutations ranked by RFECV for FCZ on F1 set.
| NO. | AdaBoost | GradientBoosting | DecisionTree | SVC_linear |
|---|---|---|---|---|
| 1 | FKS1_S639P | B9J08_003739_G672S | B9J08_003735_K325N | ERG11_K143R |
| 2 | FKBP12_S4N* | B9J08_003902_G126R | B9J08_003902_G126R | ERG11_Y132F |
| 3 | B9J08_000267_Y114D | B9J08_003902_S24P | CDR1_G995S* | ERG11_V125A |
| 4 | ERG11_Y501H* | CDR1_H771R* | ERG11_Y501H* | B9J08_004578_A202T |
| 5 | ERG11_G459S* | ERG11_Y501H* | ERG11_K143R | TAC1B_K247E |
| 6 | ERG11_K143R | B9J08_004467_ G22E | TAC1B_A651T | B9J08_004467_G22E |
| 7 | ERG11_Y132F | CDR1_G995S* | B9J08_004468_F82V | ERG11_F126L |
| 8 | B9J08_004578_M245V | TAC1B_A651T | ERG11_Y132F | B9J08_001033_L136F |
| 9 | TAC1B_E200K | ERG11_K143R | TAC1B_F214S | ERG11_Y501H* |
| 10 | TAC1B_F214S | B9J08_004468_F82V | B9J08_004467_G22E | MRR1_N647T |
| 11 | TAC1B_K247E | TAC1B_F214S | PGA7_E49D* | B9J08_004468_K506R |
| 12 | TAC1B_A583S | B9J08_003735_K325N | B9J08_000267_Y114D | B9J08_004818_D671N |
| 13 | TAC1B_A651T | ERG11_Y132F | UPC2_E229K | B9J08_004818_E749K |
| 14 | TAC1B_M653V | UPC2_E229K | TAC1B_K247E | B9J08_004578_E289G |
| 15 | B9J08_004468_F82V | B9J08_001033_L136F | B9J08_001033_L136F | B9J08_001030_E534K |
| 16 | PGA7_A18P* | B9J08_000267_Y114D | ERG11_I466M* | B9J08_000962_H59L |
| 17 | PGA7_E49D* | TAC1B_K247E | ERG10_R278H* | CDR1_E709G |
| 18 | CDR1_G995S* | B9J08_001030_E2Q | TAC1B_M653V | B9J08_004468_F82V |
| 19 | TAC1B_S195C | B9J08_003902_T917I | FKS1_S639P | B9J08_000961_K330N |
| 20 | TAC1B_S192N | PGA7_E49D* | ERG3_Y279H | FKS1_M1267I |
Bolded means previously reported mutations.
*Represents drug resistance mutation should be paid special attention to.