Table 4.

Top 20 mutations ranked by RFECV for AmB on F1 set.

NO.	AdaBoost	DecisionTree	GradientBoosting	SVC_Linear	RandomForest
1	ERG10_R278H*	ERG10_R278H*	ERG10_R278H*	ERG10_R278H*	ERG10_R278H*
2	ERG3_D283N	B9J08_003902_G126R	B9J08_003902_G126R	B9J08_003902_G126R	B9J08_003736_N36H
3	B9J08_003902_G126R	MRR1_H417L	MRR1_H417L	B9J08_005341_K374R	B9J08_003902_G126R
4	TAC1B_S195C	B9J08_000267_Y114D	B9J08_000267_Y114D	B9J08_000267_Y114D	B9J08_005338_V621F
5	B9J08_005341_A592D	ERG11_I466M*	ERG11_I466M*	ERG11_I466M*	B9J08_005341_N279H
6	B9J08_000962_G41E	ERG11_G459S*	ERG11_G459S*	ERG11_G459S*	CDR1_H771R*
7	FKS1_S639Y/S639F	ERG11_K143R	ERG11_K143R	ERG11_K143R	B9J08_000267_Y114D
8	FKS1_F219V	ERG11_Y132F	B9J08_004576_L747F	ERG11_Y132F	B9J08_001445_S430N
9	FKBP12_S4N*	B9J08_004818_S745P	B9J08_004818_S745P	TAC1B_A651T	ERG11_I466M*
10	B9J08_001033_L136F	TAC1B_A651T	B9J08_004818_P67H	PGA7_A18P	ERG11_G459S*
11	CDR1_G995S*	PGA7_A18P*	TAC1B_S192N	PGA7_E49D	ERG11_K143R
12	CDR1_E709G	TAC1B_F214S	TAC1B_A640V	CDR1_G995S*	TAC1B_A651T
13	B9J08_000267_Y114D	TAC1B_S192N	TAC1B_A651T	B9J08_005341_K918R	TAC1B_A657V
14	UPC2_E229K	B9J08_001445_L368F	TAC1B_A657V	TAC1B_K247E	PGA7_A18P*
15	B9J08_001445_L368F	TAC1B_A15T	PGA7_A18P*	TAC1B_F214S	PGA7_E49D*
16	B9J08_001445_V317L	TAC1B_A583S	B9J08_001445_L368F	TAC1B_A657V	B9J08_000166_V641D
17	ERG11_I466M*	B9J08_005341_A592D	TAC1B_S195C	B9J08_001033_L136F	ERG11_Y132F
18	ERG11_G459S*	PGA7_E49D*	B9J08_000268_I6F	B9J08_003735_E275G	UPC2_E229K
19	ERG11_K143R	ERG3_D283N	FKS1_K848R	B9J08_001030_E2Q	TAC1B_S192N
20	ERG11_Y132F	UPC2_E229K	ERG11_Y132F	CDR1_H771R*	B9J08_004818_S745P

Bolded means previously reported mutations.

*Represents drug resistance mutation should be paid special attention to.