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IC50 values for PLX51107 and PLX2853 against BET proteins.
| BET Proteins | PLX51107 | PLX2853 | ||
|---|---|---|---|---|
| IC50 (μM) a | CI95 (μM) b | IC50 (μM) a | CI95 (μM) b | |
| BRD2-BD12 | 0.052 | 0.046-0.059 | 0.0073 | 0.0035-0.015 |
| BRD4-BD12 | 0.023 | 0.021-0.026 | 0.0043 | 0.0026-0.007 |
Geometric mean of the IC50.
95% Confidence interval for geometric mean.
