The relative abundance of ARGs and int1 in different breeding stages. (A) Changes in ARGs and int1 in different breeding stages. (B–D) Changes in tetA, sul1 and blaTEM in different breeding stages. Brooding period (BP), growing period (GP), early laying period (EL), peak laying period (PL), late laying period (LL). Different letters indicate significant differences between the means (Kruskal-Wallis test; P < 0.05) of treatments. Abbreviation: ARGs, antibiotic resistance genes.