Table 3.

Memory improving and anti-Alzheimer’s disease properties of C. sativum and linalool

Extract/ Component	Type of study	Doses	Results	Ref.
Coriander volatile oil	Induced Alzheimer's disease in rats	1 and 3%	Improved and reversed the deleterious effects of amyloid ß.	(Cioanca et al., 2013 ▶)
Coriander volatile oil		1 and 3%	Enhanced the swimming time and attenuated the immobility times	(Cioanca et al., 2014 ▶)
Aqueous seed extract		0.5 mg/kg, p.o.	Restored deleterious effects on pyramidal cells.	(Enas, 2010 ▶)
Aqueous fruit extract		100, 200 and 300 mg/kg	Decreased VMA urinary levels in stress-induced animal model while, increased excretion of ascorbic acid.	(Koppula and Choi, 2012 ▶)
Leaves mixed in diet		5, 10 and 15% (w/w)	Improved memory scores in aged and young rats.	(Mani and Parle, 2009 ▶; Mani et al., 2011 ▶)
Ethanolic leaves extract		200 mg/kg; i.p.	Increased the latencies of seizure onsets which was accompanied with a decreased latency to find the platform.	(Elahdadi-Salmani et al., 2015 ▶)
Ethanolic seeds extract		100 and 200 mg/kg, p.o.	Decreased VCM, TP and OB behaviors induced by tacrine, and improved locomotor activity and cognitive functions.	(Mohan et al., 2015 ▶)
Linalool	Induced Alzheimer's disease in mice	25 mg/kg, p.o.	Showed a higher retention performance.	(Sabogal-Guáqueta et al., 2016 ▶)
Inhaled linalool		1%	The social interactions were increased.	(Linck et al., 2010 ▶)