Table 1.
A list of some of the reported studies that have shown the presence of DAMPs within EVs.
| DAMPs | Type of EVs | Disease | Source | Reference | ||
|---|---|---|---|---|---|---|
| HMGB1 | Exosome | Esophageal squamous cell carcinoma cell lines | Cell culture medium | (65) | ||
| Exosome | Hepatocellular carcinoma cell lines | Cell culture medium | (66) | |||
| Exosome | Lewis lung carcinoma (LLC) cell lines and mice model | Cell culture medium and blood | (67) | |||
| Exosome | Glioma cells | Cell culture medium | (69) | |||
| HSP60, HSP70 and HSP90 | Exosome | HepG2 hepatocellular carcinoma cells | Cell culture medium | (83) | ||
| HSP70 | Exosome | Melanoma | (84) | |||
| HSP60 and HSP70 | Exosome | NCI-H292 (human mucoepidermoid bronchial carcinoma), A549 (human lung adenocarcinoma) and K562 (human erythroleukemia) cell lines | Cell culture medium | (88) | ||
| HSP90 | Extracellular vesicles | Bladder cancer cell lines | Cell culture medium | (90) | ||
| HSP90α | Exosome | Breast cancer cell lines | Cell culture medium | (92) | ||
| Alpha crystalline and HSP22 | Exosome | Gynecological cancers | Serum | (89) | ||
| S100A9 | Exosome | Chronic lymphocytic leukemia | Plasma | (100) | ||
| S100A9 | Exosome | Polycystic ovary syndrome | Follicular fluid | (101) | ||
| S100A7A | Exosome | LIM1863 colon carcinoma cell-derived organoids | Cell culture medium | (62) | ||
| S100A5 | Microvesicle | Colorectal cancer cells | Cell culture medium | (103) | ||
| S100A12 | Extracellular Vesicles | Brain cancer cells, colorectal cancer cells, melanoma cells, kidney cancer cells | Cell culture medium | (59) | ||
| S100A4 | Extracellular vesicles | Bladder cancer cell lines and bladder cancer patients | Cell culture medium and urine | (90) | ||