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. 2021 Oct 15;12:752397. doi: 10.3389/fimmu.2021.752397

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Copyright © 2021 Kumar, Banurekha, C. P., Nancy, Padmapriyadarsini, Mary, Devi, Murhekar and Babu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Covaxin induces altered plasma levels of type Type 2/regulatory cytokines, type 1 interferons and other cytokines. (A) The plasma levels of Type 2/regulatory cytokines in Covaxin vaccinated individuals at baseline [before vaccination, M0] (n = 44) and month 1 following first dose [M1] (n = 44), month 2 following first dose [M2] (n = 44) and month 3 following first dose [M3] (n = 44). (B) The plasma levels of IL-25, IL-33 and type 1 interferons in Covaxin vaccinated individuals at baseline [before vaccination, M0] (n = 44) and month 1 following first dose [M1] (n = 44), month 2 following first dose [M2] (n = 44) and month 3 following first dose [M3] (n = 44). (C) The plasma levels of other cytokines in Covaxin vaccinated individuals at baseline [before vaccination, M0] (n = 44) and month 1 following first dose [M1] (n = 44), month 2 following first dose [M2] (n = 44) and month 3 following first dose [M3] (n = 44). The data are represented as Box and whiskers scatter plots with each circle representing a single individual, p values were calculated using the Kruskal-Wallis test t test multiple comparisons.