Table 4.
Laboratory results of diabetic survivors and non-survivors with coronavirus disease 2019
|
|
Total (n = 191)
|
Survivors (n = 165)
|
Non-survivors (n = 26)
|
P
value
|
| WBC, × 109per L | 5.94 (4.49-7.53) | 5.91 (4.42-7.29) | 7.26(5.19-13.07) | 0.016 |
| NEUT, × 109per L | 4.25 (3.13-5.37) | 4.09 (3.01-5.13) | 6.22 (3.69-11.33) | < 0.001 |
| LY, × 109per L | 1.04 (0.72-1.43) | 1.08 (0.78-1.48) | 0.65 (0.56-1.07) | < 0.001 |
| NLR | 3.85 (2.45-6.37) | 3.50 (2.33-5.53) | 10.43 (5.78-16.84) | < 0.001 |
| Hb, g/L | 127.3 ± 16.9 | 126.8 ± 16.7 | 131.6 ± 18.3 | 0.314 |
| PLT, × 109per L | 196 (147-255) | 201 (152-201) | 155 (110-230) | 0.033 |
| PCT, ng/mL | ||||
| < 0.5 | 143 (94.7) | 132 (98.5) | 11 (64.7) | < 0.001 |
| ≥ 0.5 | 8 (5.3) | 2 (1.5) | 6 (35.3) | |
| CRP | 29.8 (5.5-75.9) | 25.4 (4.4-63.0) | 115.3 (66.1-170.6) | < 0.001 |
| IL-6, pg/mL | 3.31 (1.64-17.49) | 3.09 (1.50-5.25) | 83.47 (35.75-243.60) | < 0.001 |
| PT, s | 14.30 (11.90-15.50) | 14.00 (11.60-15.40) | 16.20 (13.52-18.92) | 0.002 |
| < 16 | 116 (76.8) | 110 (81.5) | 6 (37.5) | < 0.001 |
| ≥ 16 | 35 (23.2) | 25 (18.5) | 10 (62.5) | |
| D-dimer, mg/L | 0.69 (0.35-1.35) | 0.62 (0.62-1.09) | 5.40 (1.50-21.00) | < 0.001 |
| ≤ 0.5 | 58 (37.9) | 57 (41.9) | 1 (5.9) | < 0.001 |
| > 0.5 to ≤ 1.0 | 46 (30.1) | 43 (31.6) | 3 (17.6) | |
| > 1.0 | 49 (32.0) | 36 (26.5) | 13 (76.5) | |
| ALB, g/L | 35.7 ± 5.5 | 36.0 ± 30.5 | 33.5 ± 23.4 | 0.031 |
| ALT, U/L | 23.0 (16.0-34.0) | 21.3 (15.3-32.3) | 31.0 (20.9-46.6) | 0.008 |
| AST, U/L | 29.0 (20.0-41.0) | 27.0 (19.0-38.7) | 43.0 (31.0-60.5) | < 0.001 |
| ALP, U/L | 55.0 (43.5-74.0) | 55.0 (41.5-73.0) | 57.0 (49.5-89.5) | 0.241 |
| TBIL, mmol/L | 11.3 (8.3-15.7) | 11.4 (9.0-15.1) | 11.2 (7.6-28.0) | 0.642 |
| Potassium, mmol/L | 3.88 (3.52-4.21) | 3.90 (3.54-4.21) | 3.65 (3.37-4.30) | 0.381 |
| Sodium, mmol/L | 138.4 ± 4.3 | 138.2 ± 3.9 | 139.3 ± 6.4 | 0.418 |
| Chlorine ion, mmol/L | 103.5 ± 4.9 | 103.2 ± 4.7 | 105.3 ± 6.0 | 0.052 |
| Calcium, mmol/L | 2.09 (1.95-2.17) | 2.10 (1.95-2.20) | 2.00 (1.89-2.11) | 0.042 |
| Phosphorus, mmol/L | 1.01 (0.86-1.18) | 1.02 (0.87-1.19) | 0.93 (0.76-1.18) | 0.268 |
| BUN, mmol/L | 4.70 (3.60-6.22) | 4.5 (3.59-5.82) | 6.51 (4.92-17.45) | < 0.001 |
| Creatinine, μmol/L | 66.3 (54.0-83.8) | 64.0 (44.6-81.0) | 73.0 (64.0-129.6) | 0.006 |
| UA, μmol/L | 258 (193-332) | 258 (147-321) | 293 (179-428) | 0.286 |
| CK, U/L | 66.5 (40.3-117.8) | 61.0 (36.5-111.0) | 85.0 (71.0-364.0) | 0.002 |
| LDH, U/L | 229 (180-341) | 216 (172-219) | 522 (420-611) | < 0.001 |
| Hs-cTnI > ULN, pg/mL | 10/88 (11.4) | 8/72 (11.1) | 2/16 (12.5) | 1.000 |
| TG, mmol/L | 1.39 (1.04-1.83) | 1.41 (1.05-1.98) | 1.31 (0.99-1.57) | 0.398 |
| TCH, mmol/L | 4.04 ± 1.10 | 4.12 ± 1.06 | 3.39 ± 1.16 | 0.009 |
| LDL-C, mmol/L | 2.54 ± 0.90 | 2.59 ± 0.88 | 2.10 ± 0.93 | 0.036 |
| HDL-C, mmol/L | 0.94 ± 0.26 | 0.94 ± 0.26 | 0.89 ± 0.33 | 0.450 |
| FPG, mmol/L | 9.10 (6.50-11.72) | 8.70 (6.50-11.36) | 12.00 (9.40-16.81) | 0.011 |
| 3.9-6.9 | 43 (27.7) | 40 (28.6) | 3 (20.0) | 0.0691 |
| 7.0-11.1 | 61 (39.4) | 58 (41.4) | 3 (20.0) | |
| ≥ 11.1 | 51 (32.9) | 42 (30.0) | 9 (60.0) | |
| HbA1C | 7.77 ± 1.97 | 7.61 ± 1.90 | 9.53 ± 2.02 | 0.021 |
Data are expressed as n (%), mean ± SD or median (IQR). P values were calculated by t Test, Mann-Whitney U test, χ2 test, Fisher’s exact test as appropriate.
Mann-Whitney U test comparing all subcategories.
P: Comparing groups of diabetic survivors and non-survivors; ALB: Albumin; ALP: Alkaline phosphatase; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; BUN: Urea nitrogen; CK: Creatine kinase; CRP: C reactive protein; FPG: Fasting plasma glucose; Hb: Hemoglobin; HbA1C: Glycosylated hemoglobin; HDL-C: High density lipoprotein cholesterol; Hs-cTnI: Hypersensitive troponin I; LDH: Lactate dehydrogenase; LDL-C: Low density lipoprotein cholesterol; LY: Lymphocyte; NEUT: Neutrophil; NLR: Neutrophil lymphocyte ratio; PCT: Procalcitonin; PLT: Platelet; PT: Prothrombin time; TBIL: Total bilirubin; TCH: Total cholesterol; TG: Triglyceride; UA: Uric acid; WBC: White blood cell.