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PFGE patterns of SfiI-digested DNA of C. diphtheriae strains. Lanes 1 through 4 and 6, strains of the mitis biotype, including PFGE types F (lane 1), E (lane 2), H (lane 3), L (lane 4), and J (lane 6); lanes 5 and 7 through 9, strains of the gravis biotype, including PFGE types I (lane 5), A (lane 7), M (lane 8, ATCC 13812), and N (lane 9, NCTC 10648); lane 10, combination of λ ladder and low-range PFGE size markers (kilobases).
