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. 2021 Oct 21;2021:9577874. doi: 10.1155/2021/9577874

Figure 3.

Figure 3

Effect of RTA-408 on the spinal expression of Nrf2 in the nuclear extracts of CCI mice. The spinal expression of Nrf2 in the nuclear extracts was significantly increased following CCI. RTA-408 administration further increased the spinal expression of Nrf2 in the nuclear extracts in the sham group and CCI group. Representative blots and blot density (normalized to histone H3 loading control) are presented. One-way ANOVA followed by the Bonferroni post hoc test was used for western blot results (∗∗P < 0.01, ∗∗∗P < 0.001 compared with the indicated group, n = 5 per group).