Table 2.
Comparison of the 4 different HTS systems developed as platforms for parallel screening topographies. Table adapted from [92].
| IMP | NanoTopoChip | BSSA | MARC | |
|---|---|---|---|---|
| Pattern format | Single or multiple patterns per well. 96, 384 well plate. | 2176 algorithm generated patterns on 2 cm × 2 cm area. Primitive shapes: circles, triangles etc. |
504 different patterns covering 3 mm × 3 mm area. | 6 × 6 array of 18 patterns on 2.2 cm × 2.2 cm |
| Transmission microscopy | YES | YES | NO | NO |
| High NA microscopy | YES | NO | NO | NO |
| Form factor | Tissue culture plate | Microarray chip | Microarray chip | Microarray chip |
| Automatic fluidic handling | YES | NO | NO | NO |
| Plate scanner read out | YES | NO | NO | NO |