Table 4.
List of companies that have pre-/commercialised medical implants with nanofabricated surface, and their methods of fabrication.
| Company | Technology | Fabrication method | Use |
|---|---|---|---|
| Exogenesis | nanoMesh™ 20–50 nm texture |
Cluster Ion Beam (GCIB) | Hernia repair, enhanced biocompatibility |
| Hylomorph Medical | Cellsense Microsized wells (∼1.4 μm) |
Guided assembly-based bio-lithography (GAB) | Low adhesion pouch for cardiac implantable electronic devices |
| Lepu Medical | Nano+™ ∼400 nm nanopores |
Corrosion/Oxidation | Drug eluting stents Improved early arterial healing |
| Cormatrix | CorTMPATCH Micro/nanotopography |
Decellularization | Patch for Cardiac repair |
| Straumann Group | SLActive® Ra ∼1.5 μm |
SA | Dental implants Accelerated osseointegration |
| Hiossen | ETIII NH Implant | SA | Dental implants Accelerated osseointegration |
| NuVasive | PEEK™ Pores |
Laser sintering | Spinal implants Greater neck disability index and reduced pain |
| Aesculap | PlasmaporeXP Micro/nanoscale pores |
Plasma Spraying | Spinal implants greater amount of tissue ingrowth |
| Nanovis | Nano FortiCore® 70 nm nanotubes |
Chemical Vapour Deposition and anodization | Spinal implants enhanced bone regeneration |
| Tyber Medical | BioTy™ | Plasma Spraying | Spinal implants reduced number of bacterial associated infections |