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. 2021 Oct 21;12:100152. doi: 10.1016/j.mtbio.2021.100152

Table 4.

List of companies that have pre-/commercialised medical implants with nanofabricated surface, and their methods of fabrication.

Company Technology Fabrication method Use
Exogenesis nanoMesh™
20–50 ​nm texture
Cluster Ion Beam (GCIB) Hernia repair, enhanced biocompatibility
Hylomorph Medical Cellsense
Microsized wells (∼1.4 ​μm)
Guided assembly-based bio-lithography (GAB) Low adhesion pouch for cardiac implantable electronic devices
Lepu Medical Nano+™
∼400 ​nm nanopores
Corrosion/Oxidation Drug eluting stents
Improved early arterial healing
Cormatrix CorTMPATCH
Micro/nanotopography
Decellularization Patch for Cardiac repair
Straumann Group SLActive®
Ra ∼1.5 ​μm
SA Dental implants
Accelerated osseointegration
Hiossen ETIII NH Implant SA Dental implants
Accelerated osseointegration
NuVasive PEEK™
Pores
Laser sintering Spinal implants
Greater neck disability index and reduced pain
Aesculap PlasmaporeXP
Micro/nanoscale pores
Plasma Spraying Spinal implants greater amount of tissue ingrowth
Nanovis Nano FortiCore®
70 ​nm nanotubes
Chemical Vapour Deposition and anodization Spinal implants enhanced bone regeneration
Tyber Medical BioTy™ Plasma Spraying Spinal implants reduced number of bacterial associated infections