KEY RESOURCES TABLE

REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
mouse anti-Tyrosine Hydroxylase	Immunostar	Cat#22941
goat anti-mouse Alexa 647	Invitrogen	Cat#A-21236
Bacterial and Virus Strains
AAVDJ.EF1α.DIO.ZsGreen-T2A-Kir2.1	Fuccillo Lab	N/A
AAV1.CAG.DIO.EGFP	UNC Vector Core	N/A
AAVDJ.EF1α.fDIO.Synaptophysin-mRuby2	Fuccillo Lab	N/A
AAVDJ.EF1α.DIO.Synaptophysin-EGFP	Fuccillo Lab	N/A
AAV5.hSyn.DIO.hChR2(H134R)-EFYP	UNC Vector Core	N/A
AAVDJ.EF1α.fDIO.eNpHR3.0-EYFP	Fuccillo Lab	N/A
AAVDJ.EF1α.fDIO-EYFP	Fuccillo Lab	N/A
AAVDJ.hSyn.fDIO.hM3DGq-mCherry	Stanford Virus Core	Cat#AAV-153
AAVDJ.EF1α.fDIO.mRuby2	Fuccillo Lab	N/A
AAV9.hSyn.GRAB-DA2m	Vigene	Cat#YL10013
AAVDJ.EF1α.DIO.mRuby2	Fuccillo Lab	N/A
AAVDJ.EF1α.DIO.mRuby2-Kir2.1	Fuccillo Lab	N/A
Chemicals, Peptides, and Recombinant Proteins
Dihydro-β-erythroidine (DHβE)	Tocris Bioscience	Cat#2349
Aripiprazole	Tocris Bioscience	Cat#5584
(R)-Baclofen	Tocris Bioscience	Cat#0796
CGP55845	Sigma-Aldrich	Cat#SML0594
Clozapine N-oxide	Tocris Bioscience	Cat#4936
Scopolamine hydrobromide	Sigma-Aldrich	Cat#795437
Picrotoxin	Sigma-Aldrich	Cat#P1675
d-Amphetamine	Sigma-Aldrich	Cat#A5880
Experimental Models: Organisms/Strains
Mouse: Ssttm2.1(cre)Zjh/J (SST-ires-Cre)	Jackson Laboratory	Cat#013044, RRID:IMSR_JAX:013044
Mouse: Ssttm3.1(flop)Zjh/J (SST-ires-Flp)	Jackson Laboratory	Cat#028579, RRID:IMSR_JAX:028579
Mouse: Slc6a3tm1.1(cre)Bkmn/J (DAT-IRES-Cre)	Jackson Laboratory	Cat#006660, RRID:ISMR_JAX:006660
Recombinant DNA
pAAV.EF1α.DIO.ZsGreen-T2A-Kir2.1	Byungkook Lim	N/A
pAAV.EF1α.fDIO.Synaptophysin-mRuby2	Fuccillo Lab	N/A
pAAV.EF1α.DIO.Synaptophysin-EGFP	Benjamin Arenkiel	N/A
pAAV.EF1α.fDIO.eNpHR3.0-EYFP	Theodoros Tsetsenis	N/A
pAAV.EF1α.fDIO-EYFP	Fuccillo Lab	N/A
pAAV.EF1α.fDIO.mRuby2	Fuccillo Lab	N/A
pAAV.EF1α.DIO.mRuby2	Fuccillo Lab	N/A
pAAV.EF1α.DIO.mRuby2-Kir2.1	Fuccillo Lab	N/A
Software and Algorithms
Original code for photometry analysis	Fuccillo-lab github site	DOI: 10.5281/zenodo.5026745