Kelsall 2017.

Study characteristics
Methods	Retrospective matched single‐centre cohort 1999 to2014 Nottingham Breast Institute, Nottingham City Hospital, Nottingham, United Kingdom 567 participants
Participants	Inclusion: Women with breast cancer undergoing either OPS or mastectomy and reconstruction AND the availability of PROMs data Exclusion: Previous treatment for breast cancer Delayed reconstruction Unavailability of PROMS data Surgery for prophylactic or benign disease Previous breast radiotherapy
Interventions	Intervention: Volume displacement and replacement (analysed together), (n = 286) ‐ bilateral therapeutic mammaplasty and a chest wall perforator flaps (LICAP [lateral intercostal artery perforator], LTAP [lateral thoracic artery perforator] (204) or TDAP [thoracodorsal artery perforator] (82)) Control: Mastectomy and reconstruction, (n = 281)
Outcomes	Primaryoutcomes: No outcomes of interest Secondaryoutcomes: PROMs (self‐designed)
Notes	No disclosures/funding declared