Lansu 2014.

Study characteristics
Methods	Retrospective multi‐centre cohort Regional hospitals referring to Institue Verbeeten, Netherlands July 2004 to May 2012 46 participants
Participants	Inclusion: Women over 35 years with breast cancer with tumours of stage Tis, T1 or T2, irrespective of the N stage All patients were disease‐free and alive at the moment of inclusion All patients had their last follow‐up visit < 2 years ago Patients had Karnofsky performance status 70 Exclusion: Pregnant women Poor performance status Recurrence Last follow‐up > 2 years ago
Interventions	Intervention: Volume displacement ‐ all patients had conventional RT fractionation scheme and simultaneous boost with OPS breast remodelling and careful closure by mobilising tissue, (n = 19) Control: BCS: wide local excision, all patients had conventional RT fractionation scheme and simultaneous boost, (n = 27) Other interventions not extracted: The following goups were investigated 1) The hypofractionated group (HF): hypofractionated RT fractionation scheme, sequential boost, and conventional BCS (lumpectomy). 2) The oncoplastic surgery hypofractionated group (OSHF): hypofractionated RT fractionation scheme, simultaneous boost and OPS
Outcomes	Primaryoutcomes: No outcomes of interest Secondaryoutcomes: Re‐excisions Complications PROMs Cosmetic evaluation Otheroutcomes: Margins
Notes	No disclosures/funding declared