Mansell 2017.

Study characteristics
Methods	Retrospective multi‐centre cohort June 2009 to August 2012 Glasgow Breast Units (Victoria & Western Infirmary), UK 1010 patients
Participants	Inclusion: Women with breast cancer undergoing breast‐conserving surgery or mastectomy and reconstruction Exclusion: Patients with previous DCIS or breast cancer were excluded
Interventions	Intervention: Volume displacement and volume replacement (analysed together), (n = 104) VD: (n = 90); Wise pattern reduction (78), Benelli‐type “roundblock” (6), "Racquettype” excision (3), Lejour (1), Grisotti (1) and “melon slice” reduction (1) VR: (n=14); Thoracoepigastric flap (9), breast matrix rotation (4) and thoracodorsal artery perforator (TDAP) flap (1) Control: (1) WLE (2) Mastectomy with and without reconstruction
Outcomes	Primaryoutcomes (median: (I) 56.8 months (C) 57.2 months/54.4 months Local recurrence Disease free survival Overall survival Secondaryoutcomes: Re‐excisions (extracted from Mansell 2015) Otheroutcomes: Distant recurrence Margins
Notes	Different outcomes to Mansell 2015 No disclosures/funding declared