Palsodittlir 2018.

Study characteristics
Methods	Retrospective single‐centre cohort January 2008 to Dec 2014 University of Iceland, Reykjavík, Iceland 750 participants
Participants	Inclusion: Women with breast cancer undergoing breast‐conserving surgery Exclusion: Mastectomy No tumour seen in the removed breast Bilateral surgery and males
Interventions	Intervention: Volume displacement and replacement (analysed together), (n = 85); Volume displacement (89.4%) ‐ glandular rotational flaps or the use of secondary or extended dermoglandular flaps within the breast and may often involve the use of breast reduction techniques Volume replacement (10.6%) ‐ chest wall perforator flaps (lateral intercostal artery perforator (LICAP); intercostal perforator (ICAP) or pedicled flaps (thoracodorsal artery perforator (T‐DAP) or latissimus dorsi ( LD‐miniflap) Control: standard BCS, (n = 665)
Outcomes	Primary outcomes: No outcomes of interest Secondary outcomes: Re‐excisions Complications Time to adjuvant therapy PROMs (self‐designed) Other outcomes: Length of stay Margins
Notes	No disclosures declared Funding: Visindasjoour Landspitalans (Landspitali Uni Hosp reserch fund)