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. 2021 Oct 29;2021(10):CD013658. doi: 10.1002/14651858.CD013658.pub2

Ren 2014.

Study characteristics
Methods Retrospective single‐centre matched cohort
2003 to 2013
Department of Surgery, Jiangsu Cancer Hospital, China
273 participants
Participants Inclusion:
Patients with breast cancer undergoing breast surgery with either MLDF or mastectomy with resection‐free margins (﹥1mm)
Exclusion:
Patients with multifocal diseases
Interventions Intervention:
Volume replacement ‐ mini‐LD flaps, (n = 91)
Control: Mastectomy, (n = 182)
Outcomes Primaryoutcomes (median follow‐up: (I) 83 months (C) 81 months):
  • Local recurrence

  • Overall survival


Secondaryoutcomes:
  • No outcomes of interest


Otheroutcomes:
  • Distant recurrence

Notes No disclosures/funding declared
Authors were contacted requesting full dataset for primary outcomes