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. 2021 Jun 10;2(3):315–340. doi: 10.1002/mco2.55

TABLE 1.

Genes associated with chemotherapy resistance in cancer

Drugs Comments References
Cisplatin resistance MDR1, GSH, MUTYH, MRP2, CTR1, ATOX1, ERCC1, XPF, EIF5A2, p53, Fas/CD95/APO‐1, CDKN1A, ERBB2 121 , 123 , 133 , 134 , 140 , 151 , 153 , 159 , 162 , 167
5‐FU resistance STAT3, E2F1, DPYD, TS, Id1,DPD  186 , 190 , 191 , 192 , 193 , 196
Taxol resistance BubR1, CDK5RAP2, FoxM1, EIF5A2, HER2, EDIL3 205 , 206 , 208 , 215 , 216 , 217 , 218
Oxaliplatin resistance hCTR1, DYRK2, miR‐125b, ERCC1 221 , 223 , 228 , 229
Multidrug resistance MRP, MDR1, GST‐π, Mutation of p53, Ras 233 , 234