Table 2.
Descriptive statistics of the mobile apps (N=64) containing prenatal genetic testing information.
Characteristic and category | Value, n (%) |
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Type of developer | ||||||||
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App created by commercial companies | 49 (77) |
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App created by hospitals | 11 (17) |
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App created by non-governmental organizations | 3 (5) |
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Apps created by the government (ie, California Department of Public Health) | 1 (2) |
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Operating system | ||||||||
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Android only | 15 (23) |
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iOS only | 11 (17) |
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Android and iOS | 38 (59) |
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Type of prenatal genetic tests mentioned | ||||||||
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Amniocentesis | 49 (77) |
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CVSa | 49 (77) |
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First trimester screening (NTb screening) | 46 (72) |
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Triple/quad screening | 44 (69) |
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Cell-free DNA testing or NIPTc | 35 (55) |
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Anatomy ultrasound | 26 (41) |
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Cordocentesis | 10 (16) |
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Expanded carrier screening | 8 (13) |
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First trimester screening (blood test) | 8 (13) |
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Genetic screening (prenatal) in general | 7 (11) |
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Carrier screening | 6 (9) |
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Prenatal genetic test procedures mentioned | ||||||||
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Amniocentesis | 37 (58) |
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CVS | 36 (56) |
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First trimester screening (NT screening) | 34 (53) |
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Cell-free DNA testing or NIPT | 25 (39) |
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Triple/quad screening | 17 (27) |
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Cordocentesis | 9 (14) |
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Anatomy ultrasound | 5 (8) |
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Carrier screening | 4 (6) |
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First trimester screening (blood test) | 3 (5) |
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Expanded carrier screening | 1 (2) |
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Not reported | 17 (27) |
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Timing of prenatal genetic tests mentioned | ||||||||
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CVS | 45 (70) |
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Amniocentesis | 44 (69) |
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First trimester screening (NT screening) | 40 (63) |
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Triple/quad screening | 38 (59) |
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Cell-free DNA testing or NIPT | 31 (48) |
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Anatomy ultrasound | 23 (36) |
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Cordocentesis | 9 (14) |
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First trimester screening (blood test) | 8 (13) |
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Carrier screening | 3 (5) |
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Expanded carrier screening | 1 (2) |
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Genetic screening (prenatal) in general | 1 (2) |
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Not reported | 5 (8) |
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Reliability or accuracy of prenatal genetic tests mentioned | ||||||||
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Cell-free DNA testing or NIPT | 23 (36) |
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Amniocentesis | 21 (33) |
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First trimester screening (NT screening) | 13 (20) |
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CVS | 12 (19) |
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Triple/quad screening | 12 (19) |
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Cordocentesis | 2 (3) |
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Carrier screening | 1 (2) |
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Expanded carrier screening | 1 (2) |
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First trimester screening (blood test) | 1 (2) |
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Anatomy ultrasound | 1 (2) |
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Not reported | 33 (52) |
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Interpretation of potential results of prenatal genetic tests | ||||||||
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Triple/quad screening | 19 (30) |
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Cell-free DNA testing or NIPT | 13 (20) |
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Amniocentesis | 12 (19) |
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First trimester screening (NT screening) | 9 (14) |
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Expanded carrier screening | 8 (13) |
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CVS | 8 (13) |
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Carrier screening | 3 (5) |
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Genetic screening (prenatal) in general | 1 (2) |
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Not reported | 36 (56) |
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Specific disorder(s) mentioned | ||||||||
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Trisomy 21 (Down syndrome) | 53 (83) |
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Trisomy 18 (Edward syndrome) | 33 (52) |
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Cystic fibrosis | 29 (45) |
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Trisomy 13 (Patau syndrome) | 18 (28) |
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Sickle cell anemia | 14 (22) |
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Tay-Sachs disease | 11 (17) |
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Spinal muscular atrophy | 8 (13) |
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Neural tube defect (general) | 3 (5) |
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Spina bifida | 15 (23) |
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Anencephaly | 6 (9) |
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Thalassemia | 3 (5) |
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Fragile X syndrome | 2 (3) |
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Huntington disease | 2 (3) |
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Muscular dystrophy | 2 (3) |
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Klinefelter syndrome | 1 (2) |
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Prader-Willi syndrome | 1 (2) |
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Trisomy 16 | 1 (2) |
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Turner syndrome | 1 (2) |
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Not reported | 9 (14) |
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Citation for prenatal genetic testing information | ||||||||
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No | 48 (75) |
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Yes (reliable source) | 14 (22) |
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Yes (non-reliable source) | 2 (3) |
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Costd: $0 | 64 (100) |
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Customer ratinge, mean (SD); range | 4.5 (0.6); 2.0-5.0 |
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aCVS: chorionic villus sampling.
bNT: nuchal translucency.
cNIPT: noninvasive prenatal testing.
dFive apps had an optional upgrade fee but upgrading did not affect the amount of prenatal genetic testing information available to the user.
eOnly 52 of the 64 apps (81.3%) had customer ratings.