The expression levels of prognostic hub genes are related to some clinicopathological characteristics of HCC patients. (A) The expression of all prognostic hub genes is associated with histology grade of HCC. (B) The expression of all prognostic hub genes is associated with pathological stages of HCC. (C) The expression of all prognostic hub genes is associated with T stages of HCC. (D) The expression of CENPE, SPDL1, RACGAP1, HMMR, TRIP13, CKAP2, and CKAP5 is associated with AFP level of HCC patients. (E) The expression of CENPE, SPDL1, RACGAP1, HMMR, and TRIP13 is associated with vascular invasion of HCC. (*p < 0.05; **p < 0.01; ***p < 0.001; ns, not significant).