TABLE 2.

Mutations in the gyrA QRDR of C. jejuni isolates and MICs of nalidixic acid and ciprofloxacin

Isolate no.	State health department of origin	gyrA mutation resulting in substitution at:		MIC of:
		Amino acid no. 86a	Amino acid no. 104b	Nalidixic acid	Ciprofloxacin
D125		No	No	4	0.06
D133c		No	No	8	0.125
D135		No	No	4	0.06
D2295d		No	No	4	0.03
D2589		No	No	8	0.125
D3820		No	No	8	0.125
D3836		No	No	8	0.06
D4344e		Yes	No	256	8
CS7	Oreg.	No	No	16	0.25
CS10	Conn.	No	No	16	0.25
CS17	Calif.	No	No	16	0.25
CS18	Oreg.	No	No	8	0.125
CS54	Minn.	No	No	8	0.25
CS57	Conn.	No	No	16	0.25
CS58	Conn.	No	No	8	0.125
CS59	Conn.	No	No	8	0.125
CS61	Conn.	No	No	8	0.125
CS64	Conn.	No	No	16	0.25
CS89	Calif.	No	No	8	0.125
CS120	Minn.	No	No	8	0.06
CS133	Ga.	No	No	4	0.125
CS5	Oreg.	Yes	No	512	4
CS8	Conn.	Yes	No	512	32
CS34	Minn.	Yes	No	512	32
CS40	Minn.	Yes	No	512	8
CS42	Minn.	Yes	No	512	32
CS50	Calif.	Yes	Yes	256	16
CS71	Oreg.	Yes	No	512	8
CS82	Conn.	Yes	No	512	8
CS143	Calif.	Yes	No	512	16
CS161	Ga.	Yes	No	512	32
CS165	Ga.	Yes	No	512	32
CS166	Ga.	Yes	No	256	8

^aMutants had a Thr-86-to-Ile (ACA-to-ATA) substitution. 

^bOne mutant had a Pro-104-to-Ser (CCA-to-TCA) substitution. 

^cC. jejuni subsp. jejuni ATCC 33560. 

^dC. jejuni subsp. doylei ATCC 49349. 

^eCDC C. jejuni isolate from 1992.