Table 3.

Logistic regression analysis for determining the independent predictors of poor efficacy of nonoperative management in patients with perforated peptic ulcer

Variable	OR	95%CI	P value	Adjusted OR	95%CI	P value
Age ≥ 70 yr	2.479	1.282-4.795	0.007	1.278	0.605-2.698	0.521
Male	0.658	0.344-1.260	0.207
Hypertension	1.851	0.939-3.648	0.075
Diabetes mellitus	1.954	0.898-4.253	0.091
Smoking status	1.814	0.978-3.365	0.059
Alcohol consumption	1.667	0.869-3.201	0.124
NSAIDs use	1.619	0.826-3.171	0.160
Pain duration prior to admission ≥ 12 h	2.695	1.339-5.427	0.005	2.495	1.163-5.352	0.019
Heart rate	1.018	0.998-1.037	0.071
Body temperature ≥ 38 C	2.345	0.991-5.549	0.052
Hemoglobin < 90 g/L	0.445	0.171-1.157	0.097
WBC count ≥ 12 × 109/L	1.059	0.058-2.009	0.860
Procalcitonin	1.027	1.000-1.056	0.052
CRP	1.001	1.000-1.002	0.198
Serum albumin < 30 g/L	5.331	2.876-10.635	< 0.001	5.073	2.527-10.184	< 0.001

CRP: C-reactive protein; NSAIDs: Non-steroidal anti-inflammatory drugs; PPU: Perforated peptic ulcer; WBC: White blood cell.