Figure 1. Treatment scheme for perinatal PFAS exposure.
PFAS was administered to timed-pregnant CD-1 dams during gestation (gestation day [GD] 1 to birth, or GD 18 or 19) and lactation (GD 18 or 19 to postnatal day [PND] 21). Tissues were collected from dams, as well as some male and female offspring at PND 21. Remaining offspring at PND 21 was weaned and fed the same diet as the dam. Tissues were collected from remaining pups at PND 90.