Figure 4.

PI4KIIα is not required for NMDA receptor‐dependent LTD. Similar levels of input‐specific LTD were recorded in (a) cells transfected with shRNA‐PI4KIIα (n = 8) and (b) non‐ transfected cells (n = 7). The bar indicates delivery of a pairing protocol (1 Hz for 6 min, Vh = −40 mV). Representative traces for test (black circle) and control (grey circle) pathway at time points indicated; calibration bar 50 pA/ 20 ms. Percentage of baseline depression of EPSC‐A was quantified 30 min after the pairing protocol. (c) Similar levels of input‐specific LTD of the EPSC‐N were recorded in cells transfected with shRNA‐PI4KIIα (n = 4) and control cells (data not shown), depression was quantified 30 min after the pairing protocol. Calibration bar: 30 pA/ 50 ms