Table 4.

Comparison of iTTCA-RF and state-of-the-art predictors

Tools	Tenfold CV					Independent test
	BACC (%)	AUC	Sn (%)	Sp (%)	MCC	BACC (%)	AUC	Sn (%)	Sp (%)	MCC
TTAgP1.0	63.68	0.838	70.85	56.50	0.838	68.68	0.747	78.69	58.67	0.379
iTTCA-Hybrid	78.83	0.840	85.53	72.13	0.588	70.73	0.783	82.79	58.67	0.428
iTTCA-RF	83.71	0.894	88.69	78.73	0.678	73.14	0.780	83.61	62.67	0.474

The best performance value is highlighted in bold for clarification