Table 3.

Characteristics of alternative examples of genetic results

	Malignant hyperthermia	Restless legs syndrome (RLS)/Willis-Ekbom disease
Genetic mutation	Autosomal, dominant mutation RyR1 or CACNA1S	Polygenic disorder. Various variants contribute to the phenotype
Risk (of developing the disease due to the mutation)	High risk (50%)	Slightly increased risk
Prevention possibilities	Usage of alternative anesthetic agents or muscle relaxants	No preventive measures
Treatment possibilities	If recognized promptly, treatable. Otherwise possibly lethal	Lifestyle change and medication can alleviate symptoms
Disease onset	Anytime	From childhood to over 90 years
Cure	No cure	No cure
Severity of the disease	Potentially lethal	Non-lethal