Fig. 2.

Antimonial exposure to isolates from patients with therapeutic failure boosted parasite growth. The growth curves of cure-derived (a, c, e) and failure-derived (b, d, f) isolates are shown. Black lines represent parasites maintained without Sb(III), and gray lines represent the number of parasite cells exposed to 8 µM Sb(III). Three biological replicates were assayed. Dots indicate means, and bars indicate the standard deviation. Pairwise t-tests with adjustments of the confidence level using Šidák's method were conducted for comparisons of the area under curve (AUC) of each isolate between treated and untreated samples. P-values for the comparisons are indicated in the figures. Table S2 with AUC comparisons can be found in supplementary material