Table 2.
The quantitative analysis of micro-CT for the BMP-2 release profile on rat critical-sized calvarial defect model. Data was presented as mean ± SD. Cage N = 9, Cage+Biogel N = 11, Cage +BMP-2 N = 12, Cage+Biogel+BMP-2 N = 9
| Cage (N = 9) |
Cage+Biogel (N = 11) |
Cage+BMP-2 (N = 12) |
Cage+Biogel+BMP-2 (N = 9) |
|
|---|---|---|---|---|
| BV/TV | 3.224 ± 2.503 | 2.945 ± 1.276 | 20.886 ± 7.67a,b | 23.414 ± 4.518a,b |
| BS.BV | 20.145 ± 2.36 | 19.631 ± 4.044 | 17.049 ± 2.918 | 16.73 ± 1.799 |
| Tb.Th | 0.195 ± 0.022 | 0.178 ± 0.034 | 0.194 ± 0.031 | 0.164 ± 0.012 |
| Tb.Sp | 1.74 ± 0.313 | 2.025 ± 0.282 | 0.701 ± 0.336a,b | 0.726 ± 0.168a,b |
| Tb.N | 0.166 ± 0.129 | 0.169 ± 0.077 | 1.104 ± 0.437a,b | 1.434 ± 0.304a,b |
| Tb.Pf | 5.023 ± 9.724 | −6.693 ± 8.014 | 5.34 ± 15.973 | −17.572 ± 4.28a,c |
| SMI | 2.026 ± 2.021 | −0.424 ± 1.697 | 1.935 ± 3.825 | −3.962 ± 1.533a,b,c |
| DA | 2 ± 0.473 | 2.275 ± 0.482 | 1.802 ± 0.207b | −1.718 ± 0.137b |
a compare with Cage group, p < 0.05
b compare with Cage+Biogel group, p < 0.05
c compare with Cage+BMP group, p < 0.05