Table 2.
Summary of statistical results for pulmonary tuberculosis (PTB) and extra-pulmonary tuberculosis (EPTB) clinical samples
| Test property | Summary of measure test accuracya (95%) | Test of heterogeneity | ||
|---|---|---|---|---|
|
PTB (n = 11; b3209) AUC = 0.98 |
χ2 (d.f. = 10) |
l2 | p value | |
| Sensitivity | 56(51–62) | 151.22 | 93.4 | < 0.001 |
| Specificity | 97(96–98) | 277.67 | 96.4 | < 0.001 |
| Positive likelihood ratio (PLR) | 70.73 (8.55–585.40) | 205.09 | 95.1 | < 0.001 |
| Negative likelihood ratio (PLR) | 0.43 (0.28–0.66) | 99.77 | 90.0 | < 0.001 |
| Diagnostic odd ratio (DOR) | 193.06 (51.21–727.83) | 36.66 | 72.7 | < 0.001 |
|
EPTB (n = 10; b 2327) AUC=0.99 |
X2 (d.f. = 9) |
l2 | p value | |
| Sensitivity | 87(82–91) | 47.45 | 81.00 | < 0.001 |
| Specificity | 100(99–100) | 19.19 | 53.10 | 0.0236 |
| Positive likelihood ratio (PLR) | 111.91(53.97–232.04) | 11.74 | 23.40 | 0.2282 |
| Negative likelihood ratio (PLR) | 0.15 (0.07–0.30) | 29.44 | 69.40 | 0.0005 |
| Diagnostic odd ratio (DOR) | 1337.84 (441.92–4050.12) | 13.02 | 30.90 | 0.1610 |
aRandom effects model, χ2 chi-squared, d.f. degree of freedom, I2 I-squared. b number of specimens, n number of studies, CI confidence interval, AUC area under receiver operating characteristics curve, PTB pulmonary tuberculosis, EPTB extra-pulmonary tuberculosis