Table 3.

Microfluidic systems for studying various cardiovascular diseases

Pathological condition/disease	References
Endothelial dysfunction	(Akbari et al. 2018; Mathur et al. 2019; Seo et al. 2017; Shin et al. 2019; Thomas et al. 2016; van Dijk et al. 2020; Zheng et al. 2012)
Atherosclerosis	(Chen et al. 2018; Kim et al. 2014; Menon et al. 2018; Menon et al. 2017; Park et al. 2019; Salminen et al. 2019; Shin et al. 2019; Zhang et al. 2020; Zheng et al. 2016)
Vessel stenosis (high shear stress)	(Alsmadi et al. 2017; De Lizarrondo et al. 2017; Ha and Lee 2013; Hansen et al. 2013; Jain et al. 2016; Jung and Yeom 2017; Li et al. 2012; Mannino et al. 2015; Menon et al. 2018; Menon et al. 2017; Szydzik et al. 2018; Tovar-Lopez et al. 2013; Tovar-Lopez et al. 2010; Westein et al. 2013; Xu et al. 2020; Yazdani and Karniadakis 2016)
Valve leaflet stenosis	(Osnabrugge et al. 2013)
Reversed flow (low shear stress)	(Balaguru et al. 2016; Chiu et al. 2003; Sei et al. 2017; Tovar-Lopez et al. 2019; Zarins et al. 1983)
Vessel injury	(Brown et al. 2014; de Witt et al. 2014; Gutierrez et al. 2008; Hansen et al. 2013; Herbig and Diamond 2017; Jain et al. 2016; Muthard and Diamond 2013)
Tumor growth	(Cross et al. 2010; Kim et al. 2015; Lee et al. 2014; Michelle et al. 2017; Oh et al. 2017; Sobrino et al. 2016; Zervantonakis et al. 2012)